Histoplasmosis presenting as addisonian crisis in an immunocompetent host

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Histoplasmosis presenting as addisonian crisis in an immunocompetent host.

A 71-year-old man with presumptively treated pulmonary tuberculosis ten years earlier and previous alcoholism presented with adrenal insufficiency. HIV serology was negative. A computerized tomography scan of the abdomen showed enlarged right adrenal. He recovered after emergency treatment with hydrocortisone IV. Right adrenalectomy was performed. Histoplasmosis was diagnosed and the patient wa...

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Histoplasmosis presenting as addisonian crisis in an immunocompetent host Histoplasmose apresentando-se como crise addisoniana em hospedeiro imunocompetente

A 71-year-old man with presumptively treated pulmonary tuberculosis ten years earlier and previous alcoholism presented with adrenal insufficiency. HIV serology was negative. A computerized tomography scan of the abdomen showed enlarged right adrenal. He recovered after emergency treatment with hydrocortisone IV. Right adrenalectomy was performed. Histoplasmosis was diagnosed and the patient wa...

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Histoplasmosis Presenting as a Laryngeal Ulcer in an Immunocompetent Host.

Histoplasmosis is a granulomatous disease of worldwide distribution caused by a dimorphic fungus Histoplasma capsulatum. Majority of primary infections in immunocompetent hosts are asymptomatic or may present with flu-like illness. Histoplasmosis may occur in three forms: (i) Primary acute pulmonary form, (ii) chronic pulmonary and (iii) disseminated form. The manifestations of disseminated for...

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Disseminated Histoplasmosis in an Immunocompetent Host Presenting as Pancytopenia with Bilateral Adrenal Masses

Figure 1. A) Bone marrow aspirate showing numerous Histoplasma capsulatum inside the osteoclastic giant cell and macrophage (inset) (Giemsa, 100 x), B) bone marrow biopsy showing Histoplasma (H&E, 100 x), C) PAS staining showed yeast-like cells with bright eosinophilic structures, D) GMS staining showed clusters of fungal yeasts.

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Disseminated histoplasmosis in an immunocompetent host.

Infection with histoplasma capsulatum is endemic in many parts of the world. This organism is of generally low human virulence but can act as an opportunistic agent when host immune responses allow persistent parasitization of macrophages (acute pulmonary and disseminated histoplasmosis) or when abnormal pulmonary spaces due to emphysema allow colonization of these spaces and its consequences. ...

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ژورنال

عنوان ژورنال: Revista da Sociedade Brasileira de Medicina Tropical

سال: 2004

ISSN: 0037-8682

DOI: 10.1590/s0037-86822004000100016